Gastric Mucosal Cell Proliferation in Ethanol-Induced Chronic Mucosal Injury Is Related to Oxidative Stress and Lipid Peroxidation in Rats
نویسندگان
چکیده
منابع مشابه
L-carnitine inhibits ethanol-induced gastric mucosal injury in rats.
L-carnitine is a quaternary amine that is essential for the normal oxidation of long-chain fatty acids by mitochondria. It is known that L-carnitine and its derivatives prevent the formation of reactive oxygen species, scavenge free radicals and protect cells from peroxidative stress. Oxygen-derived free radicals and lipid peroxidation products play a critical role in the pathogenesis of ethano...
متن کاملGastroprotective effects of Thymus daenensis hydroalcoholic extract against ethanol-induced gastric mucosal ulcers in rats
Background & Aim: Ulcer index is one of the most common diseases among people. Current therapies include acid secretion inhibitors which have various side effects. Herbal medicines are considered as adjuvant therapy for this disease. Hydroalcoholic extract of Thymus daenensis has various components such as flavonoids which contribute to gastroprotection. Experimental: 35 <em...
متن کاملProtective Effect of Crocin on Gastric Mucosal Lesions Induced by Ischemia-Reperfusion Injury in Rats
The present study aimed to evaluate the protective effect of crocin on gastric mucosal lesions caused by ischemia-reperfusion (I/R) injury in rats.Forty male rats were randomly divided into sham, control (I/R injury) and three crocin-pretreated groups. To induce I/R lesions, the celiac artery was clamped for 30 min and then the clamp was removed to allow reperfusion for 3 h. Pretreated-rats rec...
متن کاملProtective Effect of Crocin on Gastric Mucosal Lesions Induced by Ischemia-Reperfusion Injury in Rats
The present study aimed to evaluate the protective effect of crocin on gastric mucosal lesions caused by ischemia-reperfusion (I/R) injury in rats.Forty male rats were randomly divided into sham, control (I/R injury) and three crocin-pretreated groups. To induce I/R lesions, the celiac artery was clamped for 30 min and then the clamp was removed to allow reperfusion for 3 h. Pretreated-rats rec...
متن کاملGastroprotective effects of Thymus daenensis hydroalcoholic extract against ethanol-induced gastric mucosal ulcers in rats
Background & Aim: Ulcer index is one of the most common diseases among people. Current therapies include acid secretion inhibitors which have various side effects. Herbal medicines are considered as adjuvant therapy for this disease. Hydroalcoholic extract of Thymus daenensis has various components such as flavonoids which contribute to gastroprotection. Experimental: 35 <em...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Laboratory Investigation
سال: 2000
ISSN: 0023-6837,1530-0307
DOI: 10.1038/labinvest.3780124